Preheat the oven to 300°F. Line a large sheet pan with parchment paper, if desired.
In a large bowl, whisk together the melted butter, cinnamon, apple pie spice, brown sugar, and granulated sugar.
Add the pretzels and stir until evenly coated.
Spread the pretzels in a single layer on a large sheet pan. Use two pans if needed to avoid overcrowding.
Bake for 20 minutes, stirring halfway through.
Remove from the oven and spread the pretzels on paper towels or parchment paper to cool completely.
Once cooled, serve or store in an airtight container at room temperature for up to one week.